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2026-09-04 10:31:59 EDT+$0.03
Healthcare
Biotechnology
NASDAQ
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Tiziana Life Sciences Ltd is a biotechnology firm dedicated to the research and advancement of novel molecular therapies for human ailments, particularly ...

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$1.00
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Tiziana Life Sciences Ltd (TLSA) is a biotechnology company headquartered in London that develops therapeutic candidates centered on immunomodulation and alternative routes for immunotherapies. The company’s business model is characteristic of small, R&D-intensive biopharma: it advances drug candidates through clinical development while protecting and expanding its intellectual property portfolio through ...Tiziana Life Sciences Ltd (TLSA) is a biotechnology company headquartered in London that develops therapeutic candidates centered on immunomodulation and alternative routes for immunotherapies. The company’s business model is characteristic of small, R&D-intensive biopharma: it advances drug candidates through clinical development while protecting and expanding its intellectual property portfolio through issued patents and pending patent applications. From a product and pipeline perspective, the company highlights multiple programs that target immune pathways. Its immunology flagship program includes Foralumab (TZLS-401), described as a human anti-CD3 monoclonal antibody under development for a range of immune-mediated conditions such as Crohn’s disease, graft-versus-host disease, ulcerative colitis, multiple sclerosis, type-1 diabetes, inflammatory bowel disease, psoriasis, and rheumatoid arthritis. The company also progresses Milciclib (TZLS-201), a small-molecule inhibitor designed to suppress abnormal cell growth and cancer progression by targeting multiple kinases involved in signaling and proliferation. In addition, it develops an anti-Interleukin-6 receptor (IL6R) fully human monoclonal antibody (TZLS-501), intended to mitigate IL6-driven inflammation and address conditions such as COVID-19 patients (as described in the provided materials). In terms of services and “how it operates,” Tiziana is primarily engaged in research and development rather than manufacturing commercial products. This generally implies cost structure dominated by R&D expenses, clinical trial operations, regulatory work, and ongoing IP strategy. Financially, like many pre-revenue or development-stage biotech companies, it has valuation metrics and cash-flow dynamics that can be heavily influenced by trial progress, funding, and capital structure rather than steady operating revenue. Key leadership includes CEO and Executive Director Ivor R. Elrifi, whose background (as provided) includes senior legal/IP leadership roles in major law firms, aligning with the company’s emphasis on patents and defensible therapeutic platforms. The company also references board and leadership connections in its public communications. Overall, TLSA’s positioning is to deliver breakthrough immunomodulatory therapies by combining targeted biologics and small molecules with platform-like concepts for alternative immunotherapy routes and transformative delivery approaches, aiming to address unmet needs across immune-mediated diseases and certain neurodegenerative/neuroinflammatory indications.
Founded
2018
Employees
10
CEO
Ivor R. Elrifi
Full Name
Tiziana Life Sciences Ltd
Sector
Healthcare
Industry
Biotechnology
ROE
-125.84%
Market Cap
$0.13B
Current Ratio
8.79
WACC
6.68%
ROIC
-28.71%

Contact Information

44 20 7495 2379
14/15 Conduit Street, London W1S 2XJ

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