Traws Pharma, Inc., a biopharmaceutical firm in the clinical development stage, is dedicated to creating novel small-molecule medications delivered orally to combat ...
Traws Pharma, Inc. (NASDAQ: TRAW) is a clinical-stage biopharmaceutical company headquartered in Newtown, Pennsylvania, dedicated to developing innovative small-molecule drugs administered orally to address critical unmet medical needs in respiratory viral infections and oncology. Originally incorporated in 1998 as Onconova Therapeutics, Inc., the company rebranded to Traws Pharma in April ...Traws Pharma, Inc. (NASDAQ: TRAW) is a clinical-stage biopharmaceutical company headquartered in Newtown, Pennsylvania, dedicated to developing innovative small-molecule drugs administered orally to address critical unmet medical needs in respiratory viral infections and oncology. Originally incorporated in 1998 as Onconova Therapeutics, Inc., the company rebranded to Traws Pharma in April 2024 following a merger with Trawsfynydd, a private biotechnology firm specializing in antiviral therapeutics. This strategic move expanded Traws' portfolio to include best-in-class antivirals for influenza, COVID-19, and other infectious diseases.
The company's antiviral pipeline features two lead candidates: TRX01 (travatrelvir), an Mpro/3CL protease inhibitor being developed for COVID-19, and TRX100 (viroxavir), an endonuclease inhibitor advancing in trials for pandemic influenza. Both molecules are designed to overcome drug resistance seen with existing treatments, offering potential advantages in efficacy and safety.
In oncology, Traws is developing narazaciclib, a multi-kinase CDK4/6 inhibitor currently in Phase 1/2 clinical trials, evaluated alone or with letrozole, targeting endometrial cancer and other solid tumors. Additionally, oral rigosertib is being explored as a monotherapy or combination agent across various cancers. These programs leverage the company's expertise in kinase inhibition and drug resistance mechanisms.
As of the latest data, the company has a market capitalization of approximately $8.1 million USD, with a stock price around $0.53. It employs a small team (full-time employees reported as 4 in some sources, but LinkedIn indicates 51-200, suggesting possible discrepancy; the actual number is likely under 100). The company has no current revenue, and its financial metrics reflect a clinical-stage enterprise with substantial R&D expenditures and negative operating cash flow.
Key leadership includes CEO Iain D. Dukes, who assumed the role in October 2025 after serving as Senior Vice President; CFO Charles Parker; Chief Science Officer Dr. C. David Pauza; and Chief Medical Officer Dr. Robert R. Redfield. The company's mission is to bring transformative therapies to patients with life-threatening respiratory viral diseases and cancers, leveraging its scientific expertise and strategic partnerships.
Traws Pharma is publicly traded on the NASDAQ Global Market, with an IPO date of July 25, 2013. Despite its small size, the company has a robust pipeline and aims to advance its candidates through clinical development, with the goal of gaining regulatory approvals and commercializing its therapies to improve patient outcomes globally.
YoYYoY means Year-over-Year. It compares the latest annual value with the previous annual value to show long-term trend strength.
QoQQoQ means Quarter-over-Quarter. It compares the latest quarter with the immediately previous quarter to show short-term momentum changes.
RevenueThe total money that came through the front door from selling things, before paying a single bill. Think of it as the grand total of every credit card swipe from customers. (YoY compares this year to last year's performance, while QoQ compares the current three months to the previous three).
$2.8M
+1134.5%
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Net IncomeThe absolute bottom line. If the company paid every single supplier, employee, banker, and tax collector, this is the actual money left in their pocket at the end of the day.
$9.2M
+116.8%
+4.5%
Gross MarginThe basic markup. If they sell a $100 pair of sneakers, this percentage tells you how much of that price tag is profit right after paying for the rubber and shoelaces, but before paying for things like store rent or TV commercials.
+100.0%
+5.6%
—
Operating MarginThe 'day job' efficiency score. Out of every dollar a customer spends, this shows how many cents the company keeps after making the product AND paying for all the everyday corporate overhead (like salaries, marketing, and keeping the lights on).
-640.7%
+97.1%
—
Net MarginThe final take-home percentage. When you strip away every conceivable cost, tax, and interest payment, this is the exact number of cents the company truly gets to keep from every dollar in sales.
+328.7%
+101.4%
—
Free Cash FlowThe holy grail of corporate cash. It's the spendable, physical money left over after the business pays for its daily operations AND buys the big, expensive upgrades (like new factories or servers) it needs to survive. This is the 'free' money they can use to pay dividends or buy back stock.
$-20.8M
+30.3%
+6.6%
FCF MarginThe ultimate cash conversion rate. It shows how good the company is at turning regular sales directly into cold, hard, spendable cash. A high percentage means the business is an absolute cash-printing machine.
-744.4%
+94.4%
—
Debt / EquityThe financial risk gauge. It compares how much of the company's empire was built using borrowed money (loans) versus the owners' own money (shareholders). A high number means they are heavily leveraged and playing a riskier game; a low number means they are playing it safe.
0.0%
—
—
Current RatioThe 12-month survival check. It simply compares the cash they have right now (plus things they can quickly turn into cash) against the immediate bills they absolutely must pay this year. A score above 1 means they have enough in the wallet to cover the upcoming bills without panicking.
0.72x
-66.9%
-40.1%
Total AssetsThe absolute size of the company's empire. It bundles together absolutely everything of value they own—from the cash in the register and the inventory in the warehouse, to the software patents in the vault and the factories on the ground.
Ladies and gentlemen, thank you for standing by. Welcome to the Traws Pharma conference call. Please note all participants are in listen-only mode until the question-and-answer session. As a reminder, this call is recorded. I would now like to turn the call over to John Fraunces, LifeSci Advisors.
John FrauncesHost / Moderator, LifeSci AdvisorsSentiment 0.0
Thank you, operator, and welcome, everyone, to Traws Pharma's Full Year 2025 Financial Results and Business Update Conference Call. This afternoon, Traws issued a press release reporting its 2025 financial results and provided a business update. If you have not yet seen this press release, it is available in the Investor Relations section of the company's website. Following my introduction, we will hear from Traws's Chief Executive Officer, Dr. Iain Dukes; and Chief Financial Officer, Charles Parker. Before we begin, I would like to remind everyone that statements made during this conference call will include forward-looking statements under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, which involve risks and uncertainties that can cause actual results to differ materially. Forward-looking statements speak only as of the date they are made as the underlying facts and circumstances may change. Except as required by law, Traws disclaims any obligation to update these forward-looking statements to reflect future information, events or circumstances. For more information on forward-looking statements, please review the disclaimer in this morning's press release and the risk factors in the company's SEC filings. With that, I will now turn the call over to Traws's CEO, Dr. Iain Dukes.
Thanks, John, and thanks to everyone for joining us today. Over the last year, Traws has made substantial progress towards our objective of bringing our differentiated next-generation antiviral candidate for influenza to patients. This morning, Traws announced a private financing of $60 million. The private financing was supported by new and existing health care-focused investors. The capital from this financing positions Traws to advance the flu program through a human challenge study this summer while providing access to additional capital as we achieve further key milestones. Influenza is estimated to be a multibillion-dollar opportunity spanning prophylactic and therapeutic applications, including strategic government stockpiling and pandemic preparedness incentives. The human challenge study trial focused on flu prevention is an important step towards establishing the potential for tivoxavir marboxil as a potential best-in-class prophylactic agent for flu prevention. We intend to initiate the study this summer once we have approval received from the Medicines and Healthcare products Regulatory Agency, or MHRA, in the U.K. During today's call, we will provide an overview of development of our lead candidate, tivoxavir marboxil or tivoxavir for short, for influenza. Tivoxavir marboxil is an exciting next-generation investigational …