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$6.75
-0.30%
2026-09-04 12:37:57 EDT-$0.02
Healthcare
Biotechnology
NYSE
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Nuvation Bio Inc. functions as a clinical-stage biopharmaceutical enterprise committed to discovering and advancing therapeutic solutions for oncological conditions. Its foremost experimental ...

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Nuvation Bio, Inc. is a biotechnology and pharmaceutical company focused on discovering, developing, and commercializing medicines for difficult-to-treat cancers. The company was founded in 2018 by biopharma executive and physician David T. Hung, M.D., who is also its President and Chief Executive Officer. Hung previously founded Medivation, a company known ...Nuvation Bio, Inc. is a biotechnology and pharmaceutical company focused on discovering, developing, and commercializing medicines for difficult-to-treat cancers. The company was founded in 2018 by biopharma executive and physician David T. Hung, M.D., who is also its President and Chief Executive Officer. Hung previously founded Medivation, a company known for developing oncology medicines, and his experience is central to Nuvation Bio’s strategy of combining scientific innovation with disciplined drug development and commercial execution. Nuvation Bio is headquartered at 1500 Broadway in New York City and trades on the New York Stock Exchange under the ticker NUVB. The company has approximately 307 employees, placing it in the 201-500 employee category. Its workforce supports research, clinical development, regulatory affairs, medical affairs, commercial operations, manufacturing oversight, and corporate functions. The company describes itself as a global oncology organization focused on major unmet needs in cancer treatment. The company’s reported commercial transition followed U.S. Food and Drug Administration approval of IBTROZI in June 2025. The supplied information describes this event as a defining milestone that moved Nuvation Bio from a primarily clinical-stage organization into a commercial-stage company. Revenue associated with product commercialization is therefore becoming increasingly important, while the company continues to invest in pipeline development. The supplied financial data indicates trailing-twelve-month revenue of approximately $170 million when implied by the reported revenue multiples and enterprise value, although the exact accounting period and product-level revenue composition should be confirmed against the latest company filing. Nuvation Bio’s earlier and continuing pipeline includes NUV-422, an orally administered small molecule designed to inhibit CDK2, CDK4, and CDK6. These cyclin-dependent kinases are involved in cell-cycle regulation and are relevant to tumor growth. The pipeline has also included NUV-868, a selective BET inhibitor intended to affect epigenetic proteins involved in tumor proliferation and differentiation; NUV-569, an oral Wee1 kinase inhibitor associated with DNA-damage response biology; and NUV-1182, an antagonist of adenosine receptors. In addition, the company has described a drug-drug conjugate platform designed to deliver a PARP inhibitor together with established anticancer warheads, with particular potential applications in estrogen-receptor-positive breast cancer and ovarian cancer. The economics of Nuvation Bio are typical of an oncology pharmaceutical developer transitioning into commercialization. Costs include research personnel, laboratory and clinical-trial expenses, contract research organizations, manufacturing and analytical testing, regulatory submissions, intellectual property, sales infrastructure, and post-approval medical and commercial activities. A detailed product-level bill of materials, manufacturing recipe, unit cost, gross-to-net assumptions, or contract-manufacturing cost schedule was not provided. Consequently, no reliable product-specific BOM or cost-per-dose estimate can be stated. For a company at this stage, manufacturing may involve specialized active pharmaceutical ingredients, excipients, packaging, quality-control testing, and outsourced production, but those components should not be treated as confirmed Nuvation Bio disclosures. The supplied trailing-twelve-month financial metrics show a strong liquidity position, including a current ratio above 8 and working capital of approximately $640 million. At the same time, the company remains loss-making, with negative operating cash flow, negative free cash flow, and a negative net profit margin. Research and development and selling, general, and administrative expenses remain significant relative to revenue, reflecting continued investment in clinical programs and commercialization. The company does not currently pay a dividend. Its principal opportunities are successful commercialization of IBTROZI, expansion of its oncology pipeline, positive clinical and regulatory outcomes, and potential partnering or additional indications. Key risks include clinical failure, regulatory setbacks, competitive oncology markets, reimbursement and pricing pressure, manufacturing execution, cash utilization, dilution, and the need to demonstrate durable commercial demand.
Founded
2018
Employees
305
CEO
David T. Hung
Full Name
Nuvation Bio Inc.
Sector
Healthcare
Industry
Biotechnology
ROE
-49.73%
Market Cap
$2.37B
Current Ratio
8.37
WACC
12.26%
ROIC
-19.76%

Contact Information

332 208 6102
1500 Broadway, New York City, NY 10036

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