Trevi Therapeutics, Inc.

TRVI

$17.06

+0.06%

N/A+$0.01

Healthcare

Biotechnology

NASDAQ

Active Trading

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the advancement and commercialization of Haduvio, a potential treatment for debilitating neurologically ...

Key Metrics of TRVI

Snapshot

Latest / TTM · 6 periods

Market Cap

$2.42B

ROCE

-18.5%

EV / EBITDA

-46.37x

+8.3% YoY

FCF Yield

-1.6%

+0.7% YoY

Cash Conversion Cycle

-33257.9d

Current Ratio

37.28

Quick take

TTM —

No major risk flags in selected headline metrics.

Key Metrics

Latest / TTM · 6 periods

Valuation trend

Valuation trend table

Metric	2021	2022	2023	2024	2025	TTM
Market CapTotal market value of all shares outstanding.	$17.87M	$124.57M	$132.70M	$416.29M	$1.82B	$2.42B
Enterprise ValueCompany value including debt and cash adjustments.	$-4.33M	$121.15M	$101.65M	$383.23M	$1.80B	$2.37B
EV / SalesHow many dollars investors pay per dollar of sales.	0.00x	0.00x	0.00x	0.00x	0.00x	0.00x
EV / EBITDAValuation multiple versus operating earnings before non-cash charges.	0.13x	-4.33x	-3.56x	-8.02x	-42.14x	-46.37x
Net Debt / EBITDALeverage ratio using net debt divided by EBITDA.	0.68	0.12	1.09	0.69	0.43	1.05

Returns + ROCE gauge

ROCE latest

-18.5%

Prev year -26.9%

Returns + ROCE gauge table

Metric	2021	2022	2023	2024	2025	TTM
ROEProfit generated from shareholders' equity.	-198.8%	-27.1%	-35.2%	-48.1%	-23.3%	-23.6%
ROAProfit generated from total assets.	-88.2%	-23.7%	-32.5%	-43.2%	-22.1%	-15.5%
ROICReturn generated on invested operating capital.	-128.8%	-25.6%	-34.4%	-47.8%	-23.4%	-16.1%
ROCEOperating return on long-term capital used.	-126.1%	-27.3%	-40.6%	-51.3%	-26.9%	-18.5%
Earnings YieldEarnings as a percentage of market value.	-190.0%	-23.4%	-21.9%	-11.5%	-2.4%	-1.9%

Cash flow quality

Cash flow quality table

Metric	2021	2022	2023	2024	2025	TTM
FCFFCash flow available to all capital providers.	$-27.74M	$-27.55M	$-31.46M	$-38.29M	$-42.10M	$-52.87M
FCFECash flow available to equity holders after debt flows.	$-29.01M	$-34.17M	$-41.26M	$-38.42M	$-42.10M	$-52.87M
FCF YieldFree cash flow divided by market capitalization.	-162.0%	-22.7%	-24.0%	-9.2%	-2.3%	-1.6%
Income QualityHow well accounting earnings are backed by cash flow.	0.85	0.97	1.09	0.80	0.98	1.03
Capex / OCFShare of operating cash flow spent on capital expenditures.	0.0%	-0.6%	-0.4%	-0.1%	-0.0%	-25.2%

Operating efficiency

Operating efficiency table

Metric	2021	2022	2023	2024	2025	TTM
DSOAverage days to collect cash from customers.	0.0d	0.0d	0.0d	0.0d	0.0d	0.0d
DIOAverage days inventory stays before being sold.	0.0d	0.0d	0.0d	0.0d	0.0d	0.0d
DPOAverage days the company takes to pay suppliers.	0.0d	0.0d	0.0d	0.0d	0.0d	33257.9d
Operating CycleTime from buying inventory to collecting receivables.	0.0d	0.0d	0.0d	0.0d	0.0d	0.0d
Cash Conversion CycleNet days cash is tied in operations.	0.0d	0.0d	0.0d	0.0d	0.0d	-33257.9d

Snapshot

Latest / TTM: —

Market Cap

$2.42B

ROE

-23.6%

FCF Yield

-1.6%

Current Ratio

37.28

Supply Chain of TRVI

Upstream / Downstream / Proxies

Upstream

Keenova Therapeutics plc (f/k/a Mallinckrodt plc, merged with Endo)OTC:MNKTQUndisclosed Contract Manufacturing Organization (CMO)Undisclosed Clinical Research Organization (CRO)Vitalograph LtdRutgers, The State University of New JerseyMentiNova LLCKeenova Therapeutics plc (as IP Licensor, via Endo/Penwest legacy)OTC:MNKTQ

Downstream

No Commercial Customers (Pre-Revenue)

Proxies

Cara Therapeutics, Inc.NASDAQ:CARA Aquestive Therapeutics, Inc.NASDAQ:AQST OptiNose, Inc.NASDAQ:OPTN

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