Operating as a clinical-stage biotechnology firm, Q32 Bio Inc. is dedicated to developing biologic therapies aimed at re-establishing healthy immune equilibrium in ...
Q32 Bio Inc. is a clinical-stage biotechnology company headquartered in Waltham, Massachusetts, dedicated to developing biologic therapies that re-establish healthy immune equilibrium for patients with autoimmune and inflammatory disorders. Founded in 2017 and formerly known as AdMIRx Inc., the company changed its name to Q32 Bio in April 2020. Its ...Q32 Bio Inc. is a clinical-stage biotechnology company headquartered in Waltham, Massachusetts, dedicated to developing biologic therapies that re-establish healthy immune equilibrium for patients with autoimmune and inflammatory disorders. Founded in 2017 and formerly known as AdMIRx Inc., the company changed its name to Q32 Bio in April 2020. Its mission is to address dysfunctional immune responses by targeting potent regulators of both the innate and adaptive immune systems.
The company's pipeline includes two key investigational therapies. ADX-097, a humanized anti-C3d monoclonal antibody fusion protein, is designed to normalize complement regulation and has completed Phase I trials. It targets serious complement-driven conditions such as lupus nephritis, IgA nephropathy, C3 glomerulopathy, and ANCA-associated vasculitis, where patient needs are largely unmet. Bempikibart (ADX-914), a fully human monoclonal antibody antagonist of the interleukin-7 receptor alpha, is in Phase II trials. It aims to recalibrate adaptive immune responses by inhibiting IL-7 and TSLP signaling, offering potential treatments for atopic dermatitis and alopecia areata.
Financially, Q32 Bio is a small biotech with a market capitalization around $200 million and 24 full-time employees. The company has a strong balance sheet with a current ratio of 20.3 and minimal debt, but is pre-revenue and has negative operating cash flow, typical for clinical-stage biotechs. Research and development expenses account for a significant portion of its spending, reflecting its focus on advancing its pipeline.
Key leadership includes CEO Jodie Pope Morrison, CFO Lee Kalowski, and co-founder and CSO Dr. Shelia Violette. The team brings extensive biopharmaceutical experience from startups to commercial-stage companies. The company's vision is to act as a 'skeleton key' to open new treatment avenues for severe inflammatory and autoimmune diseases, ultimately improving patient quality of life.
YoYYoY means Year-over-Year. It compares the latest annual value with the previous annual value to show long-term trend strength.
QoQQoQ means Quarter-over-Quarter. It compares the latest quarter with the immediately previous quarter to show short-term momentum changes.
RevenueThe total money that came through the front door from selling things, before paying a single bill. Think of it as the grand total of every credit card swipe from customers. (YoY compares this year to last year's performance, while QoQ compares the current three months to the previous three).
$53.7M
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Net IncomeThe absolute bottom line. If the company paid every single supplier, employee, banker, and tax collector, this is the actual money left in their pocket at the end of the day.
$29.8M
+162.5%
-17.6%
Gross MarginThe basic markup. If they sell a $100 pair of sneakers, this percentage tells you how much of that price tag is profit right after paying for the rubber and shoelaces, but before paying for things like store rent or TV commercials.
+100.0%
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Operating MarginThe 'day job' efficiency score. Out of every dollar a customer spends, this shows how many cents the company keeps after making the product AND paying for all the everyday corporate overhead (like salaries, marketing, and keeping the lights on).
+31.5%
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Net MarginThe final take-home percentage. When you strip away every conceivable cost, tax, and interest payment, this is the exact number of cents the company truly gets to keep from every dollar in sales.
+55.5%
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Free Cash FlowThe holy grail of corporate cash. It's the spendable, physical money left over after the business pays for its daily operations AND buys the big, expensive upgrades (like new factories or servers) it needs to survive. This is the 'free' money they can use to pay dividends or buy back stock.
$-33.5M
+50.5%
+51.5%
FCF MarginThe ultimate cash conversion rate. It shows how good the company is at turning regular sales directly into cold, hard, spendable cash. A high percentage means the business is an absolute cash-printing machine.
-62.4%
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Debt / EquityThe financial risk gauge. It compares how much of the company's empire was built using borrowed money (loans) versus the owners' own money (shareholders). A high number means they are heavily leveraged and playing a riskier game; a low number means they are playing it safe.
36.5%
-89.0%
-83.0%
Current RatioThe 12-month survival check. It simply compares the cash they have right now (plus things they can quickly turn into cash) against the immediate bills they absolutely must pay this year. A score above 1 means they have enough in the wallet to cover the upcoming bills without panicking.
4.85x
-2.4%
+280.8%
Total AssetsThe absolute size of the company's empire. It bundles together absolutely everything of value they own—from the cash in the register and the inventory in the warehouse, to the software patents in the vault and the factories on the ground.