Matinas BioPharma Holdings, Inc. is a biopharmaceutical firm in the clinical development phase, dedicated to identifying and advancing a range of potential ...
Matinas BioPharma Holdings, Inc. (NYSE American: MTNB) is a clinical-stage biopharmaceutical company whose central mission is to overcome limitations of existing potent therapies by improving how medicines reach specific biological targets. The company is built around its proprietary Lipid Nanocrystal (LNC) platform technology, which is designed to deliver a broad ...Matinas BioPharma Holdings, Inc. (NYSE American: MTNB) is a clinical-stage biopharmaceutical company whose central mission is to overcome limitations of existing potent therapies by improving how medicines reach specific biological targets. The company is built around its proprietary Lipid Nanocrystal (LNC) platform technology, which is designed to deliver a broad range of therapeutic agents—such as small molecules, nucleic acids, gene therapies, vaccines, proteins, and peptides—into relevant cellular compartments. This platform approach is intended to support safer, more effective intracellular delivery compared with conventional formulations.
From a product and pipeline perspective, Matinas’ lead program includes LYPDISO, a proprietary omega-3 free fatty acid compound engineered as a prescription-grade therapy aimed at cardiovascular and metabolic disorders. The company also advances MAT2203, an orally administered version of amphotericin B that is being evaluated in Phase II clinical trials to help prevent invasive fungal infections in immunosuppressed patients. In addition, Matinas is developing MAT2501, an oral formulation of the aminoglycoside antibiotic amikacin, which has completed Phase I clinical testing with the goal of addressing multidrug-resistant bacterial infections, including non-tuberculous mycobacterium and multidrug-resistant gram-negative and intracellular pathogens.
Business-wise, Matinas operates as a development-focused biotech, meaning the company’s value creation depends heavily on clinical progress, regulatory milestones, and partnerships rather than on commercial product sales. The company also engages in collaborations—such as work involving the National Institute of Allergy and Infectious Diseases (NIAID) for antiviral development connected to remdesivir, and feasibility collaboration efforts with Genentech aimed at creating new oral drug formulations. These partnerships can help expand the applicability of its delivery technology and diversify development opportunities.
Cost and financial considerations typical for clinical-stage companies apply: significant R&D expenditures, limited or no revenue generation from marketed products, and reliance on funding mechanisms (e.g., capital raises, strategic arrangements, or milestone-based support) to sustain trials and platform development. Matinas’ balance sheet and operating metrics (as commonly reflected in market data providers) are consistent with a company in active development mode.
Leadership and key people include Jerome D. Jabbour (Co-founder, Chairman, and Chief Executive Officer), who has guided the company’s strategy and development activities. With operations commencing in 2013 and headquarters in Bedminster, New Jersey, Matinas’ near-term “wish list” would typically be to advance clinical programs efficiently, generate robust clinical/readout data, strengthen regulatory prospects, and convert platform success into multiple value-creating assets through continued partnerships and progression toward later-stage development.
YoYYoY means Year-over-Year. It compares the latest annual value with the previous annual value to show long-term trend strength.
QoQQoQ means Quarter-over-Quarter. It compares the latest quarter with the immediately previous quarter to show short-term momentum changes.
RevenueThe total money that came through the front door from selling things, before paying a single bill. Think of it as the grand total of every credit card swipe from customers. (YoY compares this year to last year's performance, while QoQ compares the current three months to the previous three).
$0
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Net IncomeThe absolute bottom line. If the company paid every single supplier, employee, banker, and tax collector, this is the actual money left in their pocket at the end of the day.
$-10.3M
+57.3%
+31.0%
Gross MarginThe basic markup. If they sell a $100 pair of sneakers, this percentage tells you how much of that price tag is profit right after paying for the rubber and shoelaces, but before paying for things like store rent or TV commercials.
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Operating MarginThe 'day job' efficiency score. Out of every dollar a customer spends, this shows how many cents the company keeps after making the product AND paying for all the everyday corporate overhead (like salaries, marketing, and keeping the lights on).
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Net MarginThe final take-home percentage. When you strip away every conceivable cost, tax, and interest payment, this is the exact number of cents the company truly gets to keep from every dollar in sales.
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Free Cash FlowThe holy grail of corporate cash. It's the spendable, physical money left over after the business pays for its daily operations AND buys the big, expensive upgrades (like new factories or servers) it needs to survive. This is the 'free' money they can use to pay dividends or buy back stock.
$-7.0M
+55.9%
-14.7%
FCF MarginThe ultimate cash conversion rate. It shows how good the company is at turning regular sales directly into cold, hard, spendable cash. A high percentage means the business is an absolute cash-printing machine.
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Debt / EquityThe financial risk gauge. It compares how much of the company's empire was built using borrowed money (loans) versus the owners' own money (shareholders). A high number means they are heavily leveraged and playing a riskier game; a low number means they are playing it safe.
28.0%
-26.5%
-99.2%
Current RatioThe 12-month survival check. It simply compares the cash they have right now (plus things they can quickly turn into cash) against the immediate bills they absolutely must pay this year. A score above 1 means they have enough in the wallet to cover the upcoming bills without panicking.
2.79x
-7.5%
-36.1%
Total AssetsThe absolute size of the company's empire. It bundles together absolutely everything of value they own—from the cash in the register and the inventory in the warehouse, to the software patents in the vault and the factories on the ground.