LENZ Therapeutics, Inc. is a biopharmaceutical firm whose primary mission involves the advancement and commercialization of new treatments designed to enhance vision ...
LENZ Therapeutics, Inc. is a pharmaceutical company dedicated to advancing ophthalmic treatments that enhance vision. The company's primary focus is on the commercialization of its lead product, VIZZ™ (aceclidine ophthalmic solution) 1.44%, which is the first and only FDA-approved aceclidine-based eye drop for presbyopia, a common age-related condition that affects ...LENZ Therapeutics, Inc. is a pharmaceutical company dedicated to advancing ophthalmic treatments that enhance vision. The company's primary focus is on the commercialization of its lead product, VIZZ™ (aceclidine ophthalmic solution) 1.44%, which is the first and only FDA-approved aceclidine-based eye drop for presbyopia, a common age-related condition that affects near vision. VIZZ™ received FDA approval in July 2025, and the company successfully launched it in the U.S. market in October 2025. The product is designed to provide rapid and sustained improvement in near vision without compromising distance vision.
Beyond VIZZ™, LENZ Therapeutics has a pipeline that includes two investigational products, LNZ100 and LNZ101, which are also being developed for presbyopia and have completed late-stage Phase III clinical trials. These products aim to offer alternative treatment options to patients, potentially with different mechanisms or durations of action.
The company operates in the biotechnology sector and is headquartered in Solana Beach, California, with its corporate operations in Del Mar, California. LENZ was founded in 2013 by James McCollum, who served as CEO until March 2021, when Evert (Eef) Schimmelpennink took over as President and CEO. Under the leadership of its experienced management team, LENZ has rapidly scaled its U.S. commercial presence and secured strategic partnerships to expand the reach of VIZZ™.
Financially, LENZ is a growth-stage biopharmaceutical company with a focus on commercial execution. As of the most recent data, the company has a market capitalization of approximately $167.6 million and employs 152 people. The company's financial metrics reflect its investment in R&D and commercialization, with a high gross profit margin of 91.2% but negative net income and operating cash flows due to significant spending on clinical development and market launch activities. However, the company maintains a strong current ratio of 10.4, indicating ample liquidity to fund its operations.
The key management team includes CEO Eef Schimmelpennink, who brings over 20 years of experience in biopharmaceuticals, and co-founder James McCollum, who remains on the board. The company's mission is to improve the quality of life for individuals with vision impairments by providing innovative, effective, and accessible treatments. With the successful launch of VIZZ™, LENZ is positioned to become a leader in the ophthalmic pharmaceutical space.
YoYYoY means Year-over-Year. It compares the latest annual value with the previous annual value to show long-term trend strength.
QoQQoQ means Quarter-over-Quarter. It compares the latest quarter with the immediately previous quarter to show short-term momentum changes.
RevenueThe total money that came through the front door from selling things, before paying a single bill. Think of it as the grand total of every credit card swipe from customers. (YoY compares this year to last year's performance, while QoQ compares the current three months to the previous three).
$19.1M
—
+188.6%
Net IncomeThe absolute bottom line. If the company paid every single supplier, employee, banker, and tax collector, this is the actual money left in their pocket at the end of the day.
$-82.1M
-65.0%
+23.1%
Gross MarginThe basic markup. If they sell a $100 pair of sneakers, this percentage tells you how much of that price tag is profit right after paying for the rubber and shoelaces, but before paying for things like store rent or TV commercials.
+96.3%
—
+152.7%
Operating MarginThe 'day job' efficiency score. Out of every dollar a customer spends, this shows how many cents the company keeps after making the product AND paying for all the everyday corporate overhead (like salaries, marketing, and keeping the lights on).
-477.5%
—
+73.2%
Net MarginThe final take-home percentage. When you strip away every conceivable cost, tax, and interest payment, this is the exact number of cents the company truly gets to keep from every dollar in sales.
-430.3%
—
+73.3%
Free Cash FlowThe holy grail of corporate cash. It's the spendable, physical money left over after the business pays for its daily operations AND buys the big, expensive upgrades (like new factories or servers) it needs to survive. This is the 'free' money they can use to pay dividends or buy back stock.
$-70.0M
-16.9%
-15.3%
FCF MarginThe ultimate cash conversion rate. It shows how good the company is at turning regular sales directly into cold, hard, spendable cash. A high percentage means the business is an absolute cash-printing machine.
-366.7%
—
+60.1%
Debt / EquityThe financial risk gauge. It compares how much of the company's empire was built using borrowed money (loans) versus the owners' own money (shareholders). A high number means they are heavily leveraged and playing a riskier game; a low number means they are playing it safe.
0.3%
-57.6%
-79.6%
Current RatioThe 12-month survival check. It simply compares the cash they have right now (plus things they can quickly turn into cash) against the immediate bills they absolutely must pay this year. A score above 1 means they have enough in the wallet to cover the upcoming bills without panicking.
14.23x
-30.1%
+30.3%
Total AssetsThe absolute size of the company's empire. It bundles together absolutely everything of value they own—from the cash in the register and the inventory in the warehouse, to the software patents in the vault and the factories on the ground.
Operator: Good afternoon, ladies and gentlemen, and welcome to the LENZ Therapeutics Second Quarter 26 Financial Results Conference Call. At this time, participants are in a listen-only mode. Following prepared remarks from management, we will conduct a question-and-answer session, and instructions will follow at that time. As a reminder, this call is being recorded. At this time, I would like to turn the call over to Daniel R. Chevallard, Chief Financial Officer. Please go ahead.
Daniel R. Chevallard: Thank you. Afternoon, and thank you for joining us today. My name is Daniel R. Chevallard, Chief Financial Officer of LENZ Therapeutics. We are joined today by Evert Schimmelpennink, our President and Chief Executive Officer Shawn Olsson, our Chief Commercial Officer and Dr. Marc Odrich, our Chief Medical Officer. Before we begin, I would like to remind you that this call will contain forward-looking statements regarding LENZ's future expectations, plans, prospects, corporate strategy, regulatory and commercial plans and expectations, cash runway projections and performance. Actual results may differ materially from those indicated by these forward-looking statements as a result of various important factors and risks including those discussed in our filings with the Securities and Exchange Commission which can also be found on our website. In addition, any forward-looking statements represent only our views as of the date of this webcast and should not be relied upon as representing our views as of any subsequent date. We specifically disclaim any obligations to update such statements. The company encourages you to consult the risk contained in our SEC filings for additional detail including our second quarter 26 Form 10 Q which is being filed today. With that, I will now turn the call over to Abe.
Evert Schimmelpennink: Thank you, Dan. Good afternoon, everyone. We are now several months post-launch. A clear view of how adoption is developing. Today, I want to share the progress we are seeing with the latest data that is helping us and how those insights are shaping our priorities for the second half of the year. Q2 reflects continued though modest growth. Encouragingly, in July, as we launched telehealth, and expanded our existing reading glass campaign on national TV we saw a significant increase in new patient starts and over 45% growth in month-over-month total prescriptions. We recognize that 1 month does not establish a trend, but these early results are consistent with the direction we hope to see. We have consistently said that the second half of the year will provide our first opportunity to assess and discuss patient persistence. Now, several quarters into launch, we have sufficient data to begin doing that. And what we are seeing is encouraging. Since launch, more than 60% of e-pharmacy patients who purchased VIZZ have purchased more than 1 multipack of VIZZ, either as part of their initial order or through a subsequent purchase. it is …