Jasper Therapeutics, Inc., a clinical-stage biotechnology company, focuses on developing therapeutics targeting mast and hematopoietic stem cell driven diseases. The company’s lead ...
Jasper Therapeutics, Inc. (JSPR) is a clinical-stage healthcare/biotechnology company headquartered in Redwood City, California. The company’s central business strategy is to translate a targeted immunology concept into therapeutic candidates—primarily briquilimab—by moving through clinical development and, ultimately, commercialization if efficacy and safety are demonstrated. At the product/program level, Jasper focuses on ...Jasper Therapeutics, Inc. (JSPR) is a clinical-stage healthcare/biotechnology company headquartered in Redwood City, California. The company’s central business strategy is to translate a targeted immunology concept into therapeutic candidates—primarily briquilimab—by moving through clinical development and, ultimately, commercialization if efficacy and safety are demonstrated.
At the product/program level, Jasper focuses on mast cell biology. Mast cells are implicated in a variety of chronic and debilitating inflammatory conditions. Jasper’s lead candidate, briquilimab, is described as a monoclonal antibody intended to block stem cell factor from binding to, and signaling through, the CD117 (c-KIT) receptor on mast and stem cells. This mechanism is positioned to address mast cell driven diseases, including chronic spontaneous urticaria and chronic inducible urticaria, as well as asthma where mast-cell mediated pathways may contribute to symptoms and exacerbations. In addition to mast cell indications, the company also discusses briquilimab as a conditioning agent concept for stem cell transplant scenarios in diseases such as sickle cell disease, Fanconi anemia, and severe combined immunodeficiency.
From a “services” perspective, a biotech like Jasper does not sell a conventional service line; instead, it “delivers” therapeutic development outcomes through internal and external capabilities: translational science, clinical operations, regulatory engagement, pharmacovigilance, and manufacturing/CMC activities coordinated for clinical supply. The effective “cost and BOM” (bill of materials) for a clinical-stage company typically revolves around R&D labor, preclinical/clinical study expenses, investigator sites, patient recruitment, trial monitoring, biologics manufacturing (cell culture/bioreactors, purification, formulation, fill-finish), and quality systems. These are usually the dominant cost drivers rather than traditional goods.
Financially, clinical-stage biotechnology firms like Jasper often operate with limited or no product revenue and instead rely on capital markets, partnerships, and ongoing financing to fund trials. The dataset provided indicates the company’s valuation and operating cash flow-related metrics can be negative (common for early-stage development), reinforcing that the key near-term value creation is tied to clinical progress, regulatory milestones, and future commercialization potential.
Key people associated with leadership include the CEO (as provided in the dataset) Jeetinder Singh Mahal, along with other senior executives such as CFO Herb Cross and other technical and operational leadership. For investors and stakeholders, the “wishes” or strategic goals typically center on: (1) generating strong clinical efficacy and safety data for briquilimab across targeted indications, (2) clarifying development pathways (trial design, endpoints, and patient populations), (3) securing adequate funding runway to reach meaningful milestones, and (4) building manufacturing readiness for scale if/when commercialization becomes feasible.
Overall, Jasper Therapeutics’ core identity is that of a focused, immunology-driven biotech aiming to convert a specific receptor-pathway intervention into therapies for chronic mast cell diseases and transplant conditioning-related needs.
YoYYoY means Year-over-Year. It compares the latest annual value with the previous annual value to show long-term trend strength.
QoQQoQ means Quarter-over-Quarter. It compares the latest quarter with the immediately previous quarter to show short-term momentum changes.
RevenueThe total money that came through the front door from selling things, before paying a single bill. Think of it as the grand total of every credit card swipe from customers. (YoY compares this year to last year's performance, while QoQ compares the current three months to the previous three).
$0
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Net IncomeThe absolute bottom line. If the company paid every single supplier, employee, banker, and tax collector, this is the actual money left in their pocket at the end of the day.
$-75.8M
-6.4%
-135.1%
Gross MarginThe basic markup. If they sell a $100 pair of sneakers, this percentage tells you how much of that price tag is profit right after paying for the rubber and shoelaces, but before paying for things like store rent or TV commercials.
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Operating MarginThe 'day job' efficiency score. Out of every dollar a customer spends, this shows how many cents the company keeps after making the product AND paying for all the everyday corporate overhead (like salaries, marketing, and keeping the lights on).
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Net MarginThe final take-home percentage. When you strip away every conceivable cost, tax, and interest payment, this is the exact number of cents the company truly gets to keep from every dollar in sales.
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Free Cash FlowThe holy grail of corporate cash. It's the spendable, physical money left over after the business pays for its daily operations AND buys the big, expensive upgrades (like new factories or servers) it needs to survive. This is the 'free' money they can use to pay dividends or buy back stock.
$-77.2M
-22.2%
+52.4%
FCF MarginThe ultimate cash conversion rate. It shows how good the company is at turning regular sales directly into cold, hard, spendable cash. A high percentage means the business is an absolute cash-printing machine.
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Debt / EquityThe financial risk gauge. It compares how much of the company's empire was built using borrowed money (loans) versus the owners' own money (shareholders). A high number means they are heavily leveraged and playing a riskier game; a low number means they are playing it safe.
29.8%
+912.1%
-14.2%
Current RatioThe 12-month survival check. It simply compares the cash they have right now (plus things they can quickly turn into cash) against the immediate bills they absolutely must pay this year. A score above 1 means they have enough in the wallet to cover the upcoming bills without panicking.
2.62x
-47.2%
-34.6%
Total AssetsThe absolute size of the company's empire. It bundles together absolutely everything of value they own—from the cash in the register and the inventory in the warehouse, to the software patents in the vault and the factories on the ground.