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Healthcare
Biotechnology
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Entera Bio Ltd. is a biopharmaceutical firm in the clinical development phase, dedicated to creating and marketing oral medications composed of large ...

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$3.00
+2.74%+$0.08
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Entera Bio Ltd. (NASDAQ: ENTX) is a clinical-stage biopharmaceutical company focused on changing how patients receive peptide and protein therapies. The company’s core thesis is that certain macromolecule medicines—such as peptides and therapeutic proteins—can be reformulated into an oral, tablet-based delivery format to improve patient convenience and potentially expand real-world ...Entera Bio Ltd. (NASDAQ: ENTX) is a clinical-stage biopharmaceutical company focused on changing how patients receive peptide and protein therapies. The company’s core thesis is that certain macromolecule medicines—such as peptides and therapeutic proteins—can be reformulated into an oral, tablet-based delivery format to improve patient convenience and potentially expand real-world adherence compared with injectable regimens. From a business perspective, Entera operates primarily in research and development and has not been described as having commercial products yet. Its revenue generation model is therefore typically associated with clinical progress, partnerships, and licensing opportunities rather than large-scale product sales. The company highlights ongoing clinical development activities for its lead programs: EB612, which is in Phase II development for hypoparathyroidism, and EB613, which has completed Phase II studies in osteoporosis and is moving through earlier-stage evaluation (Phase I) for non-healing bone fractures. This pipeline structure suggests a strategy of advancing indications based on the underlying therapeutic concept while continuing to expand the evidence base across relevant patient populations. Entera also emphasizes collaborative research and licensing. The provided information notes a collaboration arrangement with Amgen Inc. aimed at identifying and advancing potential therapeutic compounds for inflammatory conditions and other serious ailments. Such relationships can help a smaller clinical-stage firm de-risk development, access additional scientific and operational resources, and potentially broaden the therapeutic scope beyond its own internal programs. Regarding products and technology, Entera positions itself as a “leader” in orally delivered macromolecules, including peptides and other therapeutic proteins, implying proprietary formulation and delivery work that enables oral administration of large molecules. The company’s platform is effectively the differentiating “product,” with individual clinical candidates (e.g., EB612/EB613) serving as embodiments of that approach for specific indications. Cost and financial profile, based on the supplied snapshot-style metrics, appears consistent with an early, development-focused biotech: profitability metrics such as net income per share and return measures (e.g., ROA/ROE) are negative in the provided data, indicating ongoing investment and limited or no commercial revenue at the time of the snapshot. In addition, valuation and operating cash flow-related ratios are described as unfavorable/negative, which is typical for clinical-stage companies still funding trials and related R&D. Key people include CEO Miranda J. Toledano, who has served as Entera’s Chief Executive Officer since July 2022 according to the provided leadership references. The company is headquartered in Jerusalem, Israel, and employs roughly a few dozen staff (about 20 full-time employees in the provided data), which aligns with a focused R&D organization. In terms of “wishes” or near-term priorities implied by its stage, the company’s success is likely tied to clinical milestones—progressing EB612 and EB613 through additional trial phases, generating data that supports regulatory pathways for oral peptide/protein replacement therapies, and maintaining or expanding partnerships that can accelerate development and strengthen pipeline breadth.
Founded
2010
Employees
21
CEO
Miranda J. Toledano
Full Name
Entera Bio Ltd.
Sector
Healthcare
Industry
Biotechnology
ROE
-147.19%
Market Cap
$0.15B
Current Ratio
8.98
WACC
11.10%
ROIC
-84.46%

Contact Information

972 2 532 7151
Kiryat Hadassah Minrav Building, Jerusalem, JM 9112002

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