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$1.61
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2026-09-03 16:00:00 EDT-$0.04
Healthcare
Biotechnology
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CEL-SCI Corporation (CVM) focuses on the research and development of immune-based therapies to combat cancer and various infectious diseases. Its flagship immunotherapy ...

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$1.61
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CEL-SCI Corporation (NYSE American: CVM) is a public-stage biotechnology company headquartered in Vienna, Virginia. The company’s purpose is centered on developing immunotherapies that engage the body’s immune defenses to treat cancer and a variety of other diseases, including certain infectious diseases and immune-mediated conditions. CEL-SCI’s approach emphasizes using immune-system modulation ...CEL-SCI Corporation (NYSE American: CVM) is a public-stage biotechnology company headquartered in Vienna, Virginia. The company’s purpose is centered on developing immunotherapies that engage the body’s immune defenses to treat cancer and a variety of other diseases, including certain infectious diseases and immune-mediated conditions. CEL-SCI’s approach emphasizes using immune-system modulation rather than conventional small-molecule or broad-spectrum drug mechanisms. A key element of CEL-SCI’s business model is its proprietary immunotherapy platform known as LEAPS (Ligand Epitope Antigen Presentation System). LEAPS is intended to improve immune recognition by influencing antigen presentation and T-cell responses. The company develops specific LEAPS-based programs for different disease targets, including LEAPS-H1N1-DC for influenza and LEAPS COV-19 as an experimental therapy aimed at the COVID-19 coronavirus. Beyond infectious disease indications, CEL-SCI also explores immunotherapies that may be relevant to autoimmune and other immune-related conditions. CEL-SCI’s lead product candidate is Multikine (Leukocyte Interleukin, injection), which the company has advanced through clinical development; the provided overview indicates Multikine is undergoing Phase III clinical trials for head and neck cancer. The company also maintains additional therapeutic candidates in its pipeline, including CEL-2000 and CEL-4000 as potential treatments for rheumatoid arthritis. Product and program focus like this typically requires substantial research and development investment, long clinical timelines, and disciplined trial execution, all of which influence cost structure and cash burn patterns for biotech companies. From a technology and intellectual-property perspective, CEL-SCI holds patents related to its LEAPS technology and uses its scientific platform to generate multiple downstream programs. This can create portfolio value (multiple shots on goal) but also introduces operational complexity: each program can require separate clinical and regulatory milestones. Partnerships also play a role; for example, CEL-SCI has collaborated with the University of Georgia’s Center for Vaccines and Immunology to support development of its LEAPS COVID-19 immunotherapy. Cost and financial dynamics in biotech R&D companies like CEL-SCI are often characterized by heavy spend on laboratory work, clinical trial operations, and regulatory activities with revenues typically lagging behind. The provided financial snapshot metrics suggest profitability has been weak/negative in the measured period (e.g., negative return metrics and free cash flow figures), which is consistent with the funding needs of an R&D-intensive pipeline-stage company. Key people include CEO Geert R. Kersten, who has led the company since the mid-1990s, and the company’s founder Maximilian de Clara (noted as the founder in provided materials). Overall, CEL-SCI aims to improve the treatment of cancer and other diseases by leveraging the immune system’s specificity and memory, with its near-term strategic value tied closely to clinical progress and outcomes for Multikine and continued advancement of its LEAPS-based programs.
Founded
1983
Employees
43
CEO
Geert R. Kersten
Full Name
CEL-SCI Corporation
Sector
Healthcare
Industry
Biotechnology
ROE
-202.14%
Market Cap
$0.01B
Current Ratio
1.48
WACC
7.02%
ROIC
-315.58%

Contact Information

703 506 9460
8229 Boone Boulevard, Vienna, VA 22182

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