Altimmune's Phase III MASH Study Puts 2029 Data in Investor Focus
ALT has moved pemvidutide into Phase III MASH testing, with supportive mid-stage data, regulatory backing and a 2029 readout ahead.

Altimmune, Inc. is a clinical-stage biopharmaceutical company focused on pioneering treatments for obesity and various liver diseases. Its primary investigational drug, pemvidutide ...
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Est. EPS $-0.14 · Revenue $1750.00 · 5 analysts
Est. EPS $-0.16 · Revenue $1750.00 · 5 analysts
Est. EPS $-0.59 · Revenue $1875.00 · 6 analysts
Est. EPS $-0.17 · Revenue $18.49M · 3 analysts
| Metric | Latest | YoYYoY means Year-over-Year. It compares the latest annual value with the previous annual value to show long-term trend strength. | QoQQoQ means Quarter-over-Quarter. It compares the latest quarter with the immediately previous quarter to show short-term momentum changes. |
|---|---|---|---|
| RevenueThe total money that came through the front door from selling things, before paying a single bill. Think of it as the grand total of every credit card swipe from customers. (YoY compares this year to last year's performance, while QoQ compares the current three months to the previous three). | $41000 | +105.0% | — |
| Net IncomeThe absolute bottom line. If the company paid every single supplier, employee, banker, and tax collector, this is the actual money left in their pocket at the end of the day. | $-88.1M | +7.3% | -1.2% |
| Gross MarginThe basic markup. If they sell a $100 pair of sneakers, this percentage tells you how much of that price tag is profit right after paying for the rubber and shoelaces, but before paying for things like store rent or TV commercials. | +100.0% | 0.0% | — |
| Operating MarginThe 'day job' efficiency score. Out of every dollar a customer spends, this shows how many cents the company keeps after making the product AND paying for all the everyday corporate overhead (like salaries, marketing, and keeping the lights on). | -230461.0% | +55.3% | — |
| Net MarginThe final take-home percentage. When you strip away every conceivable cost, tax, and interest payment, this is the exact number of cents the company truly gets to keep from every dollar in sales. | -214861.0% | +54.8% | — |
| Free Cash FlowThe holy grail of corporate cash. It's the spendable, physical money left over after the business pays for its daily operations AND buys the big, expensive upgrades (like new factories or servers) it needs to survive. This is the 'free' money they can use to pay dividends or buy back stock. | $-67.5M | +15.4% | -15.7% |
| FCF MarginThe ultimate cash conversion rate. It shows how good the company is at turning regular sales directly into cold, hard, spendable cash. A high percentage means the business is an absolute cash-printing machine. | -164746.3% | +58.7% | — |
| Debt / EquityThe financial risk gauge. It compares how much of the company's empire was built using borrowed money (loans) versus the owners' own money (shareholders). A high number means they are heavily leveraged and playing a riskier game; a low number means they are playing it safe. | 15.9% | +1065.9% | -40.3% |
| Current RatioThe 12-month survival check. It simply compares the cash they have right now (plus things they can quickly turn into cash) against the immediate bills they absolutely must pay this year. A score above 1 means they have enough in the wallet to cover the upcoming bills without panicking. | 18.55x | +41.5% | -9.4% |
| Total AssetsThe absolute size of the company's empire. It bundles together absolutely everything of value they own—from the cash in the register and the inventory in the warehouse, to the software patents in the vault and the factories on the ground. | $279.9M | +100.9% | +57.1% |
| Metric | Annual (A vs E) | Annual Surprise | Quarter (A vs E) | Quarter Surprise |
|---|---|---|---|---|
| EPS Surprise | -1.00 vs -0.98 | -2.4% | -0.12 vs -0.14 | +11.2% |
| Revenue Surprise | $41000 vs $5556 | +637.9% | $0 vs $1750 | -100.0% |
| Date | Executive | Title | Security | Side | Shares | Price |
|---|---|---|---|---|---|---|
| Aug 13, 2026 | Durso Jerome Benedict | director, officer: President and CEO | Common Stock, par value $0.0001 | A | 15,000 | $2.95 |
| Jul 31, 2026 | WEAVER GREGORY L | officer: Chief Financial Officer | Common Stock, par value $0.0001 | A | 1,753 | $2.41 |
| Jul 31, 2026 | Roberts M Scot | officer: Chief Scientific Officer | Common Stock, par value $0.0001 | A | 875 | $2.41 |
| May 1, 2026 | Lawver Teri L | director | Stock Options (option to buy) | A | 48,800 | $2.82 |
| May 1, 2026 | Sohn Catherine A. | director | Stock Options (option to buy) | A | 48,800 | $2.82 |
Operator: Good morning, ladies and gentlemen. Welcome to the Altimmune Second Quarter 2026 Financial Results Conference Call. [Operator Instructions] As a reminder, this call is being recorded. I'm going to introduce your host for today's conference call, Luis Sanay, Vice President of Investor Relations. Luis, you may begin. Luis Sanay: Thank you, operator, and good morning, everyone. Thank you for joining us for Altimmune's second quarter 2026 financial results and business update call. On today's call, you will hear from Jerry Durso, our Chairman and Chief Executive Officer; Dr. Christophe Arbet-Engels, Chief Medical Officer; Linda Richardson, Chief Commercial Officer; and Greg Weaver, Chief Financial Officer. Following management's prepared remarks, we'll open the line for questions. Our second quarter 2026 earnings release was issued this morning and can be found in the Investor Relations section of our website. Before we begin, I would like to remind everyone that remarks made about future expectations, plans, and prospects constitute forward-looking statements for the purpose of safe harbor provisions under the Private Securities Litigation Reform Act of 1995. Altimmune cautions that these forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially from those indicated. For a review of the risk factors that could affect the company's future results and operations, we refer you to our SEC filings. I also direct you to read the forward-looking statements disclaimer in our press release issued this morning. Any statements made on this call speak only as of today's date, August 12, 2026, and the company does not undertake any obligation to update any of these forward-looking statements to reflect events or circumstances that occur on or after today's date. As a reminder, this call is being recorded and will be available for audio replay on our website. With that, I'll now turn the call over to Jerry. Jerome Durso: Good morning, everyone. Thank you for joining us today for our second quarter 2026 financial results and business update call. 2026 is proving to be a year of significant progress as Altimmune evolves into a late-stage company dedicated to serious liver diseases. We've been laser-focused on execution since the beginning of the year and believe we're well-positioned to advance our strategy and deliver on our mission. Pemvidutide is our foundation, and our confidence and conviction in its potential continues to strengthen with the growing body of clinical evidence. We're building momentum across our pemvidutide franchise and are excited for the future. Let me take a minute to highlight our recent progress. Starting with MASH, last week we announced the initiation of the PERFORMA Phase III trial as we began enrolling patients in the global program. We worked with urgency to get the trial started quickly, just 3 months after securing the financial resources to fund the study …
| Name | Title | Compensation | Gender | Year Born | Status |
|---|---|---|---|---|---|
Scot Roberts | Chief Scientific Officer | USD 683,229 | — | 1959 | Active |
Gregory L. Weaver | Chief Financial Officer | USD 619,694 | Male | 1956 | Active |
Raymond Jordt | Chief Business Officer | USD 578,850 | Male | 1973 | Active |
Christophe Arbet-Engels | Chief Medical Officer | USD 361,356 | — | 1963 | Active |
Jerome Benedict Durso | Chairman, CEO & President | USD 50,941 | Male | 1968 | Active |
Tony Blandin | Vice President of Quality & Compliance Management | — | Male | — | Active |
Andrew Shutterly | Principal Financial & Accounting Officer and Corporate Controller | — | Male | 1988 | Active |
Bertrand Georges | Chief Technology Officer | — | Male | — | Active |
Robin E. Abrams | Chief Legal Officer & Corporate Secretary | — | Female | 1964 | Active |
Linda Richardson | Chief Commercial Officer | — | Female | 1964 | Active |
ALT has moved pemvidutide into Phase III MASH testing, with supportive mid-stage data, regulatory backing and a 2029 readout ahead.

ALT's stronger cash position supports pemvidutide's MASH, AUD and ALD programs, but long timelines, funding needs and competition remain risks.

Altimmune posts a narrower Q2 loss. Its $519M in cash supports operations into 2029, while pemvidutide advances across liver and AUD studies.

Dimensional Fund Advisors LP raised its holdings in Altimmune, Inc. (NASDAQ: ALT) by 268.7% during the first quarter, according to the company in its most recent Form 13F filing with the SEC. The firm owned 1,045,926 shares of the company's stock after purchasing an additional 762,223 shares during the quarter. Dimensional Fund Advisors

Altimmune, Inc. (ALT) Q2 2026 Earnings Call Transcript
